Ovarian Cancer
2021 Year in Review - Ovarian Cancer | March 21, 2022
Findings of a retrospective study indicate that patients with platinum-sensitive recurrent ovarian cancer were increasingly being administered maintenance therapy after second-line or third-line platinum-based chemotherapy regardless of biomarker status.
2021 Year in Review - Ovarian Cancer | March 21, 2022
This review outlines the disruptions to delivery of cancer care caused by the COVID pandemic, including delays in diagnosis, surgery, and treatment, as well as the psychological impact.
2021 Year in Review - Ovarian Cancer | March 21, 2022
The findings of a prospective study suggest that immunologic response to SARS-CoV-2 vaccination is lower among patients with ovarian cancer who are receiving treatment compared with healthy volunteers, indicating that such patients should maintain precautions against COVID-19 despite vaccination.
2021 Year in Review - Ovarian Cancer | March 21, 2022
Results from a retrospective analysis indicate that health education, using a clinical nursing pathway, results in a more effective understanding of ovarian cancer, reduced psychological burden, improved sleep quality, decreased incidence of complications, improved self-care agency, and improved quality of life among patients with ovarian cancer.
2021 Year in Review - Ovarian Cancer | March 21, 2022
Results of the C-MOnGene study support the adoption of a collaborative oncogenetic model that provides flexible, patient-centered, and efficient genetic counseling and testing for hereditary breast and ovarian cancer and serves as an example for other institutions to incorporate these aspects into their oncology care.
2021 Year in Review - Ovarian Cancer | March 21, 2022
Findings of a national survey of US ovarian cancer programs identified several patient care deficits, including a greater need for the integration of palliative care, social work, dietetics, and financial counseling, and the expansion of clinical trials and genetic testing/counseling.
2021 Year in Review - Ovarian Cancer | March 21, 2022
In 2021, the COVID-19 pandemic continued to impact the practice of medicine and dissemination of treatment advances presented in scientific forums.
2021 Year in Review - Ovarian Cancer | March 21, 2022
Olaparib was more cost-effective, compared with niraparib, as maintenance therapy for patients with recurrent platinum-sensitive ovarian cancer, as determined by a model-based analysis.
2021 Year in Review - Ovarian Cancer | March 21, 2022
Results of a placebo-controlled, phase 2 study (MORAb-003-011/ENGOT-ov27) indicate that the addition of farletuzumab to platinum-based chemotherapy was not superior to placebo/chemotherapy in improving progression-free survival or other efficacy parameters in patients with platinum-sensitive recurrent ovarian cancer in first relapse who had low alemtuzumab CA-125 levels.
2021 Year in Review - Ovarian Cancer | March 21, 2022
Results of the phase 2 APPROVE trial demonstrated significant prolongation of progression-free survival with the addition of apatinib to PLD in patients with platinum-resistant or refractory recurrent ovarian cancer, with an adverse event profile consistent with that previously described for apatinib and PLD.